Browsing University Journals/ Articles by Author "Budambula, Valentine"
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Anemia Burden, Types and Associated Risk Factors among Kenyan Human Immunodeficiency Virus-1 and Mycobacterium Tuberculosis Co-infected Injection Substance Users
Abonyo, Collins; Shaviya, Nathan; Budambula, Valentine; Were, Tom (Ethiopian Journal of Health Science, 2020-09)Background Although injection substance users and individuals co-infected with Human Immunodeficiency Virus-1 and Mycobacterium tuberculosis suffer marked hematologic derangements, the rates, levels, morphologic types and ... -
Anemia Burden, Types and Associated Risk Factors among Kenyan Human Immunodeficiency Virus-1 and Mycobacterium TuberculosisCo-infected Injection Substance Users
Odiwuor, Collins; Shaviya, Nathan; Budambula, Valentine; Were, Tom (Ethiopian Journal of Health Sciences, 2020-09)BACKGROUND፡ Although injection substance users and individuals co-infected with Human Immunodeficiency Virus-1 and Mycobacterium tuberculosis suffer marked hematologic derangements, the rates, levels, morphologic types and ... -
Assemblages and Subassemblages of Giardia duodenalis in Rural Western, Kenya: Association with Sources, Signs, and Symptoms
Barasa, Erick; Indieka, Briston; Shaviya, Nathan; Osoro, Ezra; Maloba, Geofrey; Mukhongo, Denis; Budambula, Valentine; Were, Tom (Journal of Parasitology Research, 2024-02-05)Background. Giardia duodenalis causes sporadic or epidemic infections in humans. The parasite comprises assemblages A-H with A and B subdivided further into AI-IV and BI-IV subassemblages. Attempts aimed at linking these ... -
The burden and types of anaemia among HIV infected, ART-naive injection substance users in Kenya
Khazalwa, Emmanuel Mulaya; Were, Tom; Mulama, David Hughes; Budambula, Valentine (African Health Sciences, 2022-04-29)ntroduction: Illicit substance use and HIV infection cause haematological derangements. Anaemia characterized by a reduction in the quality and quantity erythrocytes is the most common disorder in both HIV-positive persons ... -
Circulating Interferon-Gamma Levels Are Associated with Low Body Weight in Newly Diagnosed Kenyan Non-Substance Using Tuberculosis Individuals
Shaviya, Nathan; Budambula, Valentine; Webale, Mark K; Were, Tom (National Library of Medicine, 2016-01-05)Although interferon-gamma, interleukin-10, and adiponectin are key immunopathogenesis mediators of tuberculosis, their association with clinical manifestations of early stage disease is inconclusive. We determined ... -
Clinical chemistry profiles in injection heroin users from Coastal Region, Kenya
Were, Tom; Wesongah, Jesca O; Munde, Elly; Ouma, Collins; Kahiga, Titus M; Owuor, Francisca Ongecha; Kiarie, James N; Ahmed, Aabid A; Makokha, Ernest P; Budambula, Valentine (BMC Clin Pathol, 2014-07-09)Background: Although the co-burden of injection drug use and HIV is increasing in Africa, little is known about the laboratory markers of injection drug use and anti-retroviral treatment (ART) in Kenyan injection drug ... -
Erratum to: Hepatitis B virus sero-profiles and genotypes in HIV-1 infected and uninfected injection and Non-injection drug users from coastal Kenya
Webale, Mark K.; Budambula, Valentine; Lihana, Raphael; Musumba, Francis O.; Nyamache, Anthony K.; Budambula, Nancy L. M.; Ahmed, Aabid A.; Ouma, Collins; Were, Tom (BMC Infectious Diseases, 2015-09-03)Erratum After publication of [1] it came to the authors’ attention that Mark K. Webale’s name was displayed incorrectly. The correct spelling of their name has been updated in the original article and is included in this erratum. -
Escherichia coli pathotypes and Shigella sero-groups in diarrheic children in Nairobi city, Kenya
Nyanga, Peter Lokamar; Onyuka, Jackson; Webale, Mark Kilongosi; Were, Tom; Budambula, Valentine (Gastroenterology and Hepatology From Bed to Bench, 2017-06-29)m: In the present study, we investigated the prevalence of E. coli pathotypes and Shigella sero-groups and their antimicrobial profiles among diarrheic children in Nairobi city, Kenya. Background: Although diarrheagenic ... -
Functional Haplotypes in the ADIPOQ Gene are Associated with Underweight, Immunosuppression and Viral Suppression in Kenyan HIV-1 Infected Antiretroviral Treatment Naive and Experienced Injection Substance Users
Shaviya, Nathan; Budambula, Valentine; Were, Tom (Ethiop J Health Sci, 2020-07-01)Background Human immunodeficiency virus and injection substance use have an influence on genes and gene expression. These effects could be beneficial or detrimental in defining disease outcomes. Adiponectin gene is key ... -
HIV-1 protease inhibitor drug resistance in Kenyan antiretroviral treatment-naive and -experienced injection drug users and non-drug users
Budambula, Valentine; Musumba, Francis O.; Webale, Mark K.; Kahiga, Titus M.; Owuor, Francisca Ongecha; Kiarie, James N.; Sowayi, George A.; Ahmed, Aabid A.; Ouma, Collins; Were, Tom (AIDS Research and Therapy, 2015-08-15)Background Although injection drug use drives antiretroviral drug resistance, the prevalence of protease inhibitor (PI) resistance among Kenyan IDUs remains undetermined. We, therefore, explored PI resistance mutations ... -
HIV-1 protease inhibitor drug resistance in Kenyan antiretroviral treatment-naive and -experienced injection drug users and non-drug users
Budambula, Valentine; Musumba, Francis O.; Webale, Mark K.; Kahiga, Titus M.; Owuor, Francisca Ongecha; Kiarie, James N.; Sowayi, George A.; Ahmed, Aabid A.; Ouma, Collins; Were, Tom (AIDS Research and Therapy, 2015-08-15)Background Although injection drug use drives antiretroviral drug resistance, the prevalence of protease inhibitor (PI) resistance among Kenyan IDUs remains undetermined. We, therefore, explored PI resistance mutations ... -
Knowledge and Associated Factors of Medical Students Regarding Radiation Exposure from Common Diagnostic Imaging Procedures at the University of Gondar, Ethiopia
Shaviya, Nathan; Budambula, Valentine; Were, Tom (Ethiopian Journal of Health Sciences, 2020-07-01)BACKGROUND: Physicians’ knowledge about radiation exposure and risks was previously reported as inadequate. Therefore, the aim of this study was to assess knowledge and associated factors regarding radiation exposure among ... -
Nutritional status of people who inject drugs in Coastal Kenya: a cross-sectional study
Budambula, Valentine; Ngari, Moses; Budambula, Nancy L.M.; Ahmed, Aabid A.; Were, Tom (BMC Nutrition, 2024-04-04)Introduction Despite documentation on injection drug use (IDU) in Kenya, the nutritional status of people who inject drugs (PWIDs) is under-explored. Elsewhere studies report under-nutrition among PWIDs which is attributed ... -
rs1445776009 variants in the human ALB gene: Association with serum albumin and clinical outcomes in HIV-infected Kenyan injection substance users
Barasa, Erick; Shaviya, Nathan; Budambula, Valentine; Were, Tom (Qassim University, 2021-04-21)Objective: The coburden of human immunodeficiency virus (HIV) and injection substance use is high especially in coastal urban and peri-urban regions of sub-Saharan Africa. Although antiretroviral treatment (ART) has improved ... -
rs1445776009 variants in the human ALB gene: Association with serum albumin and clinical outcomes in HIV-infected Kenyan injection substance users
Barasa, Erick; Shaviya, Nathan; Budambula, Valentine; Were, Tom (International Journal of Health Sciences, 2021-06-30)bjective: The coburden of human immunodeficiency virus (HIV) and injection substance use is high especially in coastal urban and peri-urban regions of sub-Saharan Africa. Although antiretroviral treatment (ART) has improved ... -
Serum adiponectin in HIV-1 and hepatitis C virus mono- and co-infected Kenyan injection drug users
Ndombi, Eric M; Budambula, Valentine; Webale, Mark K; Musumba, Francis O; Wesongah, Jesca O; Mibei, Erick; Ahmed, Aabid A; Lihana, Raphael; Were, Tom (Endocrine Connections, 2015-12)Adiponectin is an important marker of anthropometric profiles of adipose tissue. However, association of adiponectin and adiposity in HIV mono- and co-infected and hepatitis (HCV) injection drug users (IDUs) has not been ... -
Serum adiponectin in HIV-1 and hepatitis C virus mono- and co-infected Kenyan injection drug users
Ndomb, Eric M; Budambula, Valentine; Webale, Mark K; Musumba, Francis O; Wesongah, Jesca O; Mibei, Erick; Ahmed, Aabid A; Lihana, Raphael; Were, Tom (Endocrine Connections, 2015-12)Adiponectin is an important marker of anthropometric profiles of adipose tissue. However, association of adiponectin and adiposity in HIV mono- and co-infected and hepatitis (HCV) injection drug users (IDUs) has not been ... -
Socio-demographic and sexual practices associated with HIV infection in Kenyan injection and non-injection drug users
Budambula, Valentine; Matoka, Charles; Ouma, James; Ahmed, Aabid A.; Otieno, Michael F.; Were, Tom (BMC Public Health, 2018-01-30)Background Substance use is increasingly becoming prevalent on the African continent, fueling the spread of HIV infection. Although socio-demographic factors influence substance consumption and risk of HIV infection, the ...