Browsing by Author "Karim, Zachary"
Now showing items 1-2 of 2
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CD4 T-cell expression of IFN-γ and IL-17 in pediatric malarial anemia Abstract
Raballah, Evans; Kempaiah, Prakasha; Karim, Zachary; Orinda, George O.; Otieno, Michael F.; Perkins, Douglas J.; Ong’echa, John Michael (Plos one, 2017-04-20)In Plasmodium falciparum holoendemic transmission regions of western Kenya, life-threatening pediatric malaria manifests primarily as severe malarial anemia (SMA, Hb≤6.0 g/dL with any density parasitemia). To determine the ... -
Reduced Hsp70 and Glutamine in Pediatric Severe Malaria Anemia: Role of hemozoin in Suppressing Hsp70 and NF-κB Activation
Kempaiah, Prakasha; Dokladny, Karol; Karim, Zachary; Raballah, Evans; Ong’echa, John M; Moseley, Pope L; Perkins, Douglas J (Molecular Medicine, 2016-08-30)Severe malarial anemia (SMA; hemoglobin [Hb] <5.0 g/dL) is a leading global cause of morbidity and mortality among children residing in Plasmodium falciparum transmission regions. Exploration of molecular pathways through ...