Browsing by Author "Ong’echa, John M"
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Interleukin (IL)-13 promoter polymorphisms (-7402 T/G and -4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels
Okeyo, Winnie A; Munde, Elly O; Okumu, Wilson; Raballah, Evans; Anyona, Samuel B; Vulule, John M; Ong’echa, John M; Perkins, Douglas J; Ouma, Collins (BMC Immunology, 2013-03-25)In holoendemic Plasmodium falciparum transmission areas such as western Kenya, severe malarial anemia [SMA, hemoglobin (Hb) < 6.0 g/dL, with any density parasitemia] is the most common clinical manifestation of severe ... -
Interleukin (IL)-13 promoter polymorphisms (-7402 T/G and -4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels
Okeyo, Winnie A; Munde, Elly O; Okumu, Wilson; Raballah, Evans; Anyona, Samuel B; Vulule, John M; Ong’echa, John M; Perkins, Douglas J; Ouma, Collins (BMC Imunology, 2013-03-25)n holoendemic Plasmodium falciparum transmission areas such as western Kenya, severe malarial anemia [SMA, hemoglobin (Hb) < 6.0 g/dL, with any density parasitemia] is the most common clinical manifestation of severe malaria ... -
Interleukin (IL)-13 promoter polymorphisms (-7402 T/G and -4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels.
Okeyo, Winnie A; Munde, Elly O; Okumu, Wilson; Raballah, Evans; Anyona, Samuel B; Vulule, John M; Ong’echa, John M; Perkins, Douglas J; Ouma, Collins (BMC Immunology, 2013-03-13)In holoendemic Plasmodium falciparum transmission areas such as western Kenya, severe malarial anemia [SMA, hemoglobin (Hb) < 6.0 g/dL, with any density parasitemia] is the most common clinical manifestation of severe ... -
Reduced Hsp70 and Glutamine in Pediatric Severe Malaria Anemia: Role of hemozoin in Suppressing Hsp70 and NF-κB Activation
Kempaiah, Prakasha; Dokladny, Karol; Karim, Zachary; Raballah, Evans; Ong’echa, John M; Moseley, Pope L; Perkins, Douglas J (Molecular Medicine, 2016-08-30)Severe malarial anemia (SMA; hemoglobin [Hb] <5.0 g/dL) is a leading global cause of morbidity and mortality among children residing in Plasmodium falciparum transmission regions. Exploration of molecular pathways through ...