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SARS-CoV-2 origin, myths and diagnostic technology developments
(Egyptian Journal of Medical Human Genetics, 2022-03-04)
Background
After the first case of COVID-19 being announced in China in December 2019, various diagnostic technologies have been developed at unprecedented pace with the aim of providing a basis for accurate clinical ...
Stocking Density Induced Stress on Plasma Cortisol and Whole Blood Glucose Concentration in Nile Tilapia Fish (Oreochromis niloticus) of Lake Victoria, Kenya
(International Journal of Zoology, 2020-07-17)
Effects of high stocking densities (HSDs) were evaluated for Nile tilapia fish (Oreochromis niloticus) under culture to determine its influence on plasma cortisol and whole blood glucose concentration. Plasma cortisol ...
Mutational signatures for breast cancer diagnosis using artificial intelligence
(Journal of the Egyptian National Cancer Institute, 2023-05-15)
Background
Breast cancer is the most common female cancer worldwide. Its diagnosis and prognosis remain scanty, imprecise, and poorly documented. Previous studies have indicated that some genetic mutational signatures are ...
Spatial Variations in Aquatic Insect Community Structure in the Winam Gulf of Lake Victoria, Kenya
(International Journal of Ecology, 2023-09-08)
Background. Aquatic insect community structure is dynamic due to threats by anthropogenic activities coupled with changing climatic conditions. The insect’s survival is dependent on the substrate, water quality, and ...
Whole Transcriptome Analysis of Differentially Expressed Genes in Cultured Nile Tilapia (O. niloticus) Subjected to Chronic Stress Reveals Signaling Pathways Associated with Depressed Growth
(MDPI Gene, 2023-03-25)
Chronic stress is a serious threat to aquaculture as it lowers fish growth performance and compromises fish welfare. The exact mechanism by which growth is retarded is, however, not clearly understood. This study sought ...
Contraindications of Batch Staining in Malaria Diagnosis and its implications on Drug and Vaccine Protective Efficacy
(Elixir International Journal, 2013-05-13)
The primary objective was to evaluate if batch staining of malaria blood films results in false
positive smears. False positive smears (>1%) may cause a serious underestimate of a drug’s
or vaccine’s protective efficacy, ...
In-silico analysis of potent Mosquirix vaccine adjuvant leads
(Journal of Genetic Engineering and Biotechnology, 2023-11-30)
Background
World Health Organization recommend the use of malaria vaccine, Mosquirix, as a malaria prevention strategy. However, Mosquirix has failed to reduce the global burden of malaria because of its inefficacy. The ...
The Potential of DNA Barcode-Based Delineation Using Seven Putative Candidate Loci of the Plastid Region in Inferring Molecular Diversity of Cowpea at Sub-Species Level.
(American Journal of Molecular Biology, 2016-10)
The novelty and suitability of the mitochondrial gene CO1 in DNA barcoding as a reliable identification tool in animal species are undisputed. This is attributed to its standardized sequencing segment of the mitochondrial ...
Ebola Virus Disease, Diagnostics and Therapeutics: Where is the Consensus in Over Three Decades of Clinical Research?
(Scientific African, 2021-07-22)
Ebola virus is a neglected tropical disease widely accepted as one of the most fatal diseases of human and nonhuman primates ever encountered in recent years. For a long time, development of vaccines and anti-Ebola drugs ...
Pangenomics of the cichlid species (Oreochromis niloticus) reveals genetic admixture ancestry with potential for aquaculture improvement in Kenya
(The Journal of Basic and Applied Zoology, 2023-10-08)
Background Nile tilapia has a variety of phenotypes suitable for aquaculture farming, yet its entire gene pool with potential for breeding climate ready strains in resource-limited settings remains scanty and poorly ...