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    Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya 

    Munde, Elly O.; Okeyo, Winnie A.; Raballah, Evans; Anyona, Samuel B.; Were, Tom; Ong’echa, John M.; Perkins, Douglas J.; Ouma, Collins (BMC Infectious Diseases, 2017-04-20)
    Background Naturally-acquired immunity to Plasmodium falciparum malaria develops after several episodes of infection. Fc gamma receptors (FcγRs) bind to immunoglobulin G (IgG) antibodies and mediate phagocytosis of opsonized ...
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    Haplotype of non-synonymous mutations within IL-23R is associated with susceptibility to severe malaria anemia in a P. falciparum holoendemic transmission area of Kenya 

    Munde, Elly O.; Raballah, Evans; Okeyo, Winnie A.; Ong’echa, John M.; Perkins, Douglas J.; Ouma, Collins (BMC Infectious Diseases volume, 2017-04-20)
    Background Improved understanding of the molecular mechanisms involved in pediatric severe malarial anemia (SMA) pathogenesis is a crucial step in the design of novel therapeutics. Identification of host genetic susceptibility ...
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    CD4 T-cell expression of IFN-γ and IL-17 in pediatric malarial anemia Abstract 

    Raballah, Evans; Kempaiah, Prakasha; Karim, Zachary; Orinda, George O.; Otieno, Michael F.; Perkins, Douglas J.; Ong’echa, John Michael (Plos one, 2017-04-20)
    In Plasmodium falciparum holoendemic transmission regions of western Kenya, life-threatening pediatric malaria manifests primarily as severe malarial anemia (SMA, Hb≤6.0 g/dL with any density parasitemia). To determine the ...

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    Author
    Perkins, Douglas J. (3)
    Raballah, Evans (3)Munde, Elly O. (2)Okeyo, Winnie A. (2)Ong’echa, John M. (2)Ouma, Collins (2)Anyona, Samuel B. (1)Karim, Zachary (1)Kempaiah, Prakasha (1)Ong’echa, John Michael (1)... View MoreSubjectCD4 T-cell, expression , IFN-γ, IL-17, pediatric, malarial, anemia (1)Fcγ receptor IIA, IIIA ,IIIB, genetic, polymorphisms severe malaria, anemia, children (1)Haplotype , non-synonymous, mutations, IL-23R , associated, susceptibility,severe, malaria, anemia , P. falciparum, holoendemic, transmission (1)... View MoreDate Issued
    2017 (3)
    Has File(s)Yes (3)

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