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    Genome Sequence of a Staphylococcus xylosus Clinical Isolate, Strain SMA0341-04 (UGA5), from Siaya County Referral Hospital in Siaya, Kenya 

    Cheng, Qiuying; Xie, Gary; Daligault, Hajnalka; Davenport, Karen; Gleasner, Cheryl; Jacobs, Lindsey; Kubicek-Sutherland, Jessica; LeCuyer, Tessa; Otieno, Vincent; Raballah, Evans; Doggett, Norman; McMahon, Benjamin; Perkins, Douglas J.; Mukundan, Harshini (ASM Journals, 2019-04-18)
    We report here the genome sequence of a Staphylococcus xylosus clinical isolate, strain SMA0341-04 (UGA5), which contains one chromosome and at least one plasmid. Notably, strain SMA0341-04 (UGA5) contains the tetracycline ...
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    Genetic variation in interleukin-7 is associated with a reduced erythropoietic response in Kenyan children infected with Plasmodium falciparum 

    Kisia, Lily E.; Kempaiah, Prakasha; Anyona, Samuel B.; Munde, Elly O.; Achieng, Angela O.; Ong’echa, John M.; Lambert, Christophe G.; Chelimo, Kiprotich; Ouma, Collins; Perkins, Douglas J; Raballah, Evans (BMC Med Genet., 2019-08-16)
    Background Severe malarial anemia (SMA) is a leading cause of malaria-related morbidity and mortality in children. The genetic factors that influence development of SMA and inefficient erythropoiesis, a central pathogenic ...
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    Direct detection of bacteremia by exploiting host-pathogen interactions of lipoteichoic acid and lipopolysaccharide 

    Kubicek-Sutherland, Jessica Z.; Vu, Dung M.; Aneesa, Noormohamed; Mendez, Heather M.; Stromberg, Loreen R.; Pedersen, Christine A.; Hengartner, Astrid C.; Klosterman, Katja E.; Haley, A. Bridgewater; Otieno, Vincent; Cheng, Qiuying; Anyona, Samuel B.; Ouma, Collins; Raballah, Evans; Perkins, Douglas J.; McMahon, Benjamin H.; Mukundan, Harshini (Scientific Reports, 2019-04-17)
    Bacteremia is a leading cause of death in sub-Saharan Africa where childhood mortality rates are the highest in the world. The early diagnosis of bacteremia and initiation of treatment saves lives, especially in high-disease ...
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    Cyclooxygenase-2 haplotypes influence the longitudinal risk of malaria and severe malarial anemia in Kenyan children from a holoendemic transmission region. 

    Anyona, Samuel B; Hengartner, Nicolas W; Raballah, Evans; Ong'echa, John Michael; Lauve, Nick; Cheng, Qiuying; Fenimore, Paul W; Ouma, Collins; Lambert, Christophe G; McMahon, Benjamin H; Perkins, Douglas J (Journal of Human Genetics, 2019-10-29)
    Cyclooxygenase-2 [(COX-2) or prostaglandin endoperoxide H2 synthase-2 (PTGS-2)] induces the production of prostaglandins as part of the host-immune response to infections. Although a number of studies have demonstrated the ...
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    Draft Genome Sequences of Two Staphylococcus warneri Clinical Isolates, Strains SMA0023-04 (UGA3) and SMA0670-05 (UGA28), from Siaya County Referral Hospital, Siaya, Kenya. 

    Xie, Gary; Cheng, Qiuying; Daligault, Hajnalka; Davenport, Karen; Gleasner, Cheryl; Jacobs, Lindsey; Kubicek-Sutherland, Jessica; LeCuyer, Tessa; Otieno, Vincent; Raballah, Evans; Doggett, Norman; Mukundan, Harshini; Perkins, Douglas J.; McMahon, Benjamin (ASM Journals, 2019-04-11)
    We report the complete draft genome sequences of two Staphylococcus warneri clinical isolates, strains SMA0023-04 (UGA3) and SMA0670-05 (UGA28), each of which contains one chromosome and at least one plasmid. Isolate ...
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    Genome Sequences of a Staphylococcus aureus Clinical Isolate, Strain SMA0034-04 (UGA22), from Siaya County Referral Hospital in Siaya, Kenya 

    Xie, Gary; Cheng, Qiuying; Daligault, Hajnalka; Davenport, Karen; Gleasner, Cheryl; Jacobs, Lindsey; Sutherland, Jessica Kubicek; LeCuyer, Tessa; Otieno, Vincent; Raballah, Evans; Mukundan, Harshini; Perkins, Douglas J; McMahon, Benjamin; Doggett, Norman (ASM Journals, 2019-04-25)
    Here, we report the genome sequences of a Staphylococcus aureus clinical isolate, strain SMA0034-04 (UGA22), which contains one chromosome and one plasmid. We also reveal that isolate SMA0034-04 (UGA22) contains loci in ...
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    Integrated OMICS platforms identify LAIR1 genetic variants as novel predictors of cross-sectional and longitudinal susceptibility to severe malaria and all-cause mortality in Kenyan children 

    Achieng, Angela O.; Hengartner, Nicolas W.; Raballah, Evans; Cheng, Qiuying; Anyona, Samuel B.; Lauve, Nick; Guyah, Bernard; Foo-Hurwitz, Ivy; Ong'echa, John M.; McMahon, Benjamin H.; Ouma, Collins; Lambert, Christophe G.; Perkinsa, Douglas J. (EBioMedicine, 2019-07-02)
    Background Severe malarial anaemia (SMA) is a leading cause of childhood mortality in holoendemic Plasmodium falciparum regions. Methods To gain an improved understanding of SMA pathogenesis, whole genome and transcriptome ...
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    The diagnostic accuracy of Th1 (IFN-γ, TNF-α, and IL-2) and Th2 (IL-4, IL-6 and IL-10) cytokines response in AFB microscopy smear negative PTB- HIV co-infected patients 

    Kisuya, Job; Chemtai, Alex; Raballah, Evans; Keter, Alfred; Ouma, Collins (Microbiology Resource Announcements, 2019-04)
    Acid Fast Bacilli (AFB) microscopy smear remains the most widely used laboratory diagnostic technique for Pulmonary Tuberculosis (PTB) in low-and-middle income countries. Although it is highly specific, the sensitivity ...
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    Genome Sequence of Staphylococcus pettenkoferi Strain SMA0010-04 (UGA20), a Clinical Isolate from Siaya County Referral Hospital in Siaya, Kenya 

    Otieno, Vincent; Xie, Gary; Cheng, Qiuying; Daligault, Hajnalka; Davenport, Karen; Gleasner, Cheryl; Jacobs, Lindsey; Kubicek-Sutherland, Jessica; LeCuyer, Tessa; Raballah, Evans; Doggett, Norman; Mukundan, Harshini; McMahon, Benjamin; Perkins, Douglas J (Microbiology Resource Announcements, 2019-04-25)
    Here, we report the sequence of a Staphylococcus pettenkoferi clinical isolate, strain SMA0010-04 (UGA20), which contains the PC1 beta-lactamase (blaZ) gene.

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    Raballah, Evans (9)
    Cheng, Qiuying (7)Mukundan, Harshini (5)Otieno, Vincent (5)Ouma, Collins (5)Daligault, Hajnalka (4)Davenport, Karen (4)Doggett, Norman (4)Gleasner, Cheryl (4)Jacobs, Lindsey (4)... View MoreSubjectCyclooxygenase-2, haplotypes, longitudinal, risk , malaria ,severe ,malarial, anemia, Kenyan, children, holoendemic ,transmission, region (1)Diagnostic, accuracy, Th1 (IFN-γ, TNF-α, and IL-2) Th2 (IL-4, IL-6 ,IL-10) cytokines, response , AFB, microscopy, smear, negative, PTB- HIV co-infected, patients (1)Direct, detection, bacteremia, exploiting, host-pathogen, interactions, lipoteichoic, acid, lipopolysaccharide (1)Draft, Genome, Sequences , Two Staphylococcus warneri ,Clinical, Isolates, Strains SMA0023-04 (UGA3) , SMA0670-05 (UGA28), (1)Genetic, variation, interleukin-7, associated , reduced, erythropoietic, response, Kenyan, children, infected, Plasmodium, falciparum (1)Genome, Sequence ,Staphylococcus, pettenkoferi, Strain, SMA0010-04 (UGA20), Clinical, Isolate (1)Genome, Sequence ,Staphylococcus, xylosus ,Clinical, Isolate, Strain SMA0341-04 (UGA5), (1)Genome, Sequences , Staphylococcus, aureus, Clinical, Isolate, Strain SMA0034-04 (UGA22), (1)Integrated, OMICS, platforms, identify, LAIR1, genetic, variants , novel, predictors, cross-sectional, longitudinal, susceptibility, severe malaria , all-cause, mortality (1)... View MoreDate Issued
    2019 (9)
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