Browsing University Journals/ Articles by Author "Sowayi, George"
Now showing items 1-7 of 7
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Cytokine profiles in highly active antiretroviral treatment non-adherent, adherent and naive HIV-1 infected patients in Western Kenya
Musa, Fauzia; Shaviya, Nathan; Mambo, Fidelis; Abonyo, Collins; Barasa, Erick; Wafula, Philemon; Sowayi, George; Barasa, Mustafa; Were, Tom (African Health Sciences, 2021-12)Background: Cytokines play an important role in signaling the immune system to build an adequate immune response against HIV. HIV distorts the balance between pro and anti-inflammatory cytokines causing viral replication. ... -
Distribution of hemoglobinopathy phenotypes in western Kenya: a retrospective study done at Aga Khan Hospital, Kisumu
Mutua, Benard; Sowayi, George; Okoth, Patrick (The Egyptian Journal of Internal Medicine, 2022-06-07)Background Hemoglobinopathies are inheritable disorders of hemoglobin and are the most common genetic defects in humans. This is a neglected public health problem whose undiagnosis remain a major threat to its prevention ... -
High-performance liquid chromatography local reference ranges of hemoglobin fractions (HbA, HbA2, and HbF) in detection of hemoglobinopathies in western Kenya
Mutua, Benard; Chelangat, Rose; Mustafa, Barasa; Were, Tom; Makani, Julie; Sowayi, George; Okoth, Patrick (The Egyptian Journal of Internal Medicine, 2022-12-29)Background Western Kenya, being a malaria-endemic region, has a high prevalence of hemoglobinopathies mostly sickle cell and thalassemia. The hemoglobin fractions or variants, HbA, HbA2, and HbF, serve as biomarkers for ... -
Prevalence of Non-Tuberculosis Mycobacterium Pulmonary Disease in HIV-1 Patients with Presumptive Pulmonary Tuberculosis in Western Kenya
Ochayo, Anne; Wamalwa, Ronald; Barasa, Erick; Zablon, Jeremiah; Sowayi, George; Were, Tom; Gitonga, Godfrey; Shaviya, Nathan (Ethiopian Journal of Health Sciences, 2023-09-21)Background: Non-tuberculous mycobacteria (NTMs) are ubiquitous, free-living, environmental saprophytic microorganisms. NTMs belong to the genus Mycobacterium which includes Mycobacterium tuberculosis (MTB). NTMs have ... -
Prognostic Potential of RDW in Discriminating Hemoglobinopathies among Patients reporting to Aga Khan Hospital, Kisumu
Mutua, Benard; Sowayi, George; Okoth, Patrick (Egyptian Journal of Medical Human Genetics, 2022-08-13)Background Red cell distribution width (RDW) measures the extent of variation in red blood cell (RBC) volume in terms of coefficient of variation. It reflects the degree of variation in RBC’s sizes and shapes, characteristic ... -
Red cell distribution width as a surrogate marker of haemoglobinopathies in western Kenya
Mutua, Benard M.; Sowayi, George; Okoth, Patrick (African Journal of Laboratory Medicine, 2022-04-29)distribution width (RDW) measures anisopoikiloytosis and is readily reported by haematology analysers as a complete blood count parameter. The utility of RDW as a diagnostic marker of haemoglobinopathies in Kenya remains ... -
Stability and Kinetics Studies Using an RP- HPLC-UV Method Developed for Assays of Salvianolic Acid A Degradation as a Therapeutic
Munyendo, Were L. L.; Baraza, Lilechi D.; Sowayi, George (International Research Journal of Pure and Applied Chemistry, 2015-03-13)Aims: To evaluate the stability of Salvianolic acid A (SAA), a promising cardiovascular drug candidate. Additionally avail an archetype in-vitro therapeutic monitoring from SAA degradation profile for characteristic oral ...