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    CD4 T-cell expression of IFN-γ and IL-17 in pediatric malarial anemia Abstract 

    Raballah, Evans; Kempaiah, Prakasha; Karim, Zachary; Orinda, George O.; Otieno, Michael F.; Perkins, Douglas J.; Ong’echa, John Michael (Plos one, 2017-04-20)
    In Plasmodium falciparum holoendemic transmission regions of western Kenya, life-threatening pediatric malaria manifests primarily as severe malarial anemia (SMA, Hb≤6.0 g/dL with any density parasitemia). To determine the ...
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    Human NCR3 gene variants rs2736191 and rs11575837 alter longitudinal risk for development of pediatric malaria episodes and severe malarial anemia 

    Olewe, Perez K.; Awandu, Shehu Shagari; Munde, Elly O.; Anyona, Samuel B.; Raballah, Evans; Amolo, Asito S.; Ogola, Sidney; Ndenga, Erick; Onyango, Clinton O.; Rochford, Rosemary; Perkins, Douglas J.; Ouma, Collins (BMC Cancer, 2023-06-20)
    Background Epstein Barr virus (EBV)-associated endemic Burkitt’s Lymphoma pediatric cancer is associated with morbidity and mortality among children resident in holoendemic Plasmodium falciparum regions in western Kenya. ...
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    Genetic variation in CSF2 (5q31.1) is associated with longitudinal susceptibility to pediatric malaria, severe malarial anemia, and all-cause mortality in a high-burden malaria and HIV region of Kenya 

    Kisia, Lily E.; Cheng, Qiuying; Raballah, Evans; Munde, Elly O.; McMahon, Benjamin H.; Hengartner, Nick W.; Ong’echa, John M.; Chelimo, Kiprotich; Lambert, Christophe G.; Ouma, Collins; Kempaiah, Prakasha; Perkins, Douglas J.; Schneider, Kristan A.; Anyona, Samuel B. (Tropical Medicine and Health, 2022-06-25)
    Plasmodium falciparum infections remain among the leading causes of morbidity and mortality in holoendemic transmission areas. Located within region 5q31.1, the colony-stimulating factor 2 gene (CSF2) encodes granulocyte ...
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    Differential Gene Expression in Host Ubiquitination Processes in Childhood Malarial Anemia 

    Anyona, Samuel B.; Raballah, Evans; Cheng, Qiuying; Hurwitz, Ivy; Ndege, Caroline; Munde, Elly; Otieno, Walter; Seidenberg, Philip D.; Schneider, Kristan A.; Lambert, Christophe G.; McMahon, Benjamin H.; Ouma, Collins; Perkins, Douglas J. (Frontiers in Genetics, 2021-11-22)
    Background: Malaria remains one of the leading global causes of childhood morbidity and mortality. In holoendemic Plasmodium falciparum transmission regions, such as western Kenya, severe malarial anemia [SMA, hemoglobin ...
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    Changes in the frequencies of Plasmodium falciparum dhps and dhfr drug-resistant mutations in children from Western Kenya from 2005 to 2018: the rise of Pfdhps S436H 

    Pacheco, M. Andreína; Schneider, Kristan A.; Cheng, Qiuying; Munde, Elly O.; Ndege, Caroline; Onyango, Clinton; Raballah, Evans; Anyona, Samuel B.; Ouma, Collins; Perkins, Douglas J.; Escalante, Ananias A. (Malaria Journal, 2020-10-22)
    Background Sulfadoxine-pyrimethamine (SP) is the only anti-malarial drug formulation approved for intermittent preventive treatment in pregnancy (IPTp). However, mutations in the Plasmodium falciparum dhfr (Pfdhfr) and ...
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    Ingestion of hemozoin by peripheral blood mononuclear cells alters temporal gene expression of ubiquitination processes 

    Anyona, Samuel B.; Cheng, Qiuying; Raballah, Evans; Hurwitz, Ivy; Lambert, Christophe G.; McMahon, Benjamin H.; Ouma, Collins; Perkins, Douglas J. (Biochemistry and Biophysics Reports, 2022-01-11)
    Plasmodium falciparum (Pf) malaria is among the leading causes of childhood morbidity and mortality worldwide. During a natural infection, ingestion of the malarial parasite product, hemozoin (PfHz), by circulating phagocytic ...
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    Perkins, Douglas J. (16)
    Raballah, Evans (16)Ouma, Collins (13)Anyona, Samuel B. (11)Cheng, Qiuying (11)Munde, Elly O. (9)McMahon, Benjamin H. (7)Schneider, Kristan A. (6)Lambert, Christophe G. (5)Mukundan, Harshini (4)... View MoreSubjectCD4 T-cell, expression , IFN-γ, IL-17, pediatric, malarial, anemia (1)Changes , frequencies, Plasmodium, falciparum, dhps , dhfr drug-resistant, mutations, children ,Western, Kenya from 2005 to 2018: the rise of Pfdhps S436H (1)Changes,frequencies,Plasmodium, falciparum, dhps, dhfr, drug-resistant, mutations, children, Western 2005, 2018, rise, Pfdhps S436H (1)Comparative, genomic , phenotypic, characterization ,invasive, non-typhoidal ,Salmonella, isolates (1)Differential, Gene, Expression, Host, Ubiquitination, Processes, Childhood, Malarial, Anemia (1)Direct, detection, bacteremia, exploiting, host-pathogen, interactions, lipoteichoic, acid, lipopolysaccharide (1)Draft, Genome, Sequences , Two Staphylococcus warneri ,Clinical, Isolates, Strains SMA0023-04 (UGA3) , SMA0670-05 (UGA28), (1)Fcγ receptor IIA, IIIA ,IIIB, genetic, polymorphisms severe malaria, anemia, children (1)Genetic variation, CSF2 (5q31.1), associated, longitudinal, susceptibility, pediatric, malaria, severe malaria,l anemia, cause mortality, high-burden, malaria, HIV, region (1)Genome, Sequence ,Staphylococcus, xylosus ,Clinical, Isolate, Strain SMA0341-04 (UGA5), (1)... View MoreDate Issued2017 (3)2019 (3)2022 (3)2023 (3)2020 (2)2021 (2)Has File(s)Yes (16)

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