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    Genome Sequences of a Staphylococcus aureus Clinical Isolate, Strain SMA0034-04 (UGA22), from Siaya County Referral Hospital in Siaya, Kenya 

    Xie, Gary; Cheng, Qiuying; Daligault, Hajnalka; Davenport, Karen; Gleasner, Cheryl; Jacobs, Lindsey; Sutherland, Jessica Kubicek; LeCuyer, Tessa; Otieno, Vincent; Raballah, Evans; Mukundan, Harshini; Perkins, Douglas J; McMahon, Benjamin; Doggett, Norman (ASM Journals, 2019-04-25)
    Here, we report the genome sequences of a Staphylococcus aureus clinical isolate, strain SMA0034-04 (UGA22), which contains one chromosome and one plasmid. We also reveal that isolate SMA0034-04 (UGA22) contains loci in ...
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    CD4 T-cell expression of IFN-γ and IL-17 in pediatric malarial anemia Abstract 

    Raballah, Evans; Kempaiah, Prakasha; Karim, Zachary; Orinda, George O.; Otieno, Michael F.; Perkins, Douglas J.; Ong’echa, John Michael (Plos one, 2017-04-20)
    In Plasmodium falciparum holoendemic transmission regions of western Kenya, life-threatening pediatric malaria manifests primarily as severe malarial anemia (SMA, Hb≤6.0 g/dL with any density parasitemia). To determine the ...
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    Factors associated with non-adherence to Artemisinin-based combination therapy (ACT) to malaria in a rural population from holoendemic region of western Kenya 

    Onyango, Elizabeth O; Ayodo, George; Watsierah, Carren A; Were, Tom; Okumu, Wilson; Anyona, Samuel B; Raballah, Evans; Okoth, John M; Gumo, Sussy; Orinda, George O; Ouma, Collins (National Library of Medicine, 2012-06-24)
    Background: Over the years, reports implicate improper anti-malarial use as a major contributor of morbidity and mortality amongst millions of residents in malaria endemic areas, Kenya included. However, there are limited ...
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    Human NCR3 gene variants rs2736191 and rs11575837 alter longitudinal risk for development of pediatric malaria episodes and severe malarial anemia 

    Olewe, Perez K.; Awandu, Shehu Shagari; Munde, Elly O.; Anyona, Samuel B.; Raballah, Evans; Amolo, Asito S.; Ogola, Sidney; Ndenga, Erick; Onyango, Clinton O.; Rochford, Rosemary; Perkins, Douglas J.; Ouma, Collins (BMC Cancer, 2023-06-20)
    Background Epstein Barr virus (EBV)-associated endemic Burkitt’s Lymphoma pediatric cancer is associated with morbidity and mortality among children resident in holoendemic Plasmodium falciparum regions in western Kenya. ...
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    Interleukin (IL)-13 promoter polymorphisms (-7402 T/G and -4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels. 

    Okeyo, Winnie A; Munde, Elly O; Okumu, Wilson; Raballah, Evans; Anyona, Samuel B; Vulule, John M; Ong’echa, John M; Perkins, Douglas J; Ouma, Collins (BMC Immunology, 2013-03-13)
    In holoendemic Plasmodium falciparum transmission areas such as western Kenya, severe malarial anemia [SMA, hemoglobin (Hb) < 6.0 g/dL, with any density parasitemia] is the most common clinical manifestation of severe ...
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    Integrated OMICS platforms identify LAIR1 genetic variants as novel predictors of cross-sectional and longitudinal susceptibility to severe malaria and all-cause mortality in Kenyan children 

    Achieng, Angela O.; Hengartner, Nicolas W.; Raballah, Evans; Cheng, Qiuying; Anyona, Samuel B.; Lauve, Nick; Guyah, Bernard; Foo-Hurwitz, Ivy; Ong'echa, John M.; McMahon, Benjamin H.; Ouma, Collins; Lambert, Christophe G.; Perkinsa, Douglas J. (EBioMedicine, 2019-07-02)
    Background Severe malarial anaemia (SMA) is a leading cause of childhood mortality in holoendemic Plasmodium falciparum regions. Methods To gain an improved understanding of SMA pathogenesis, whole genome and transcriptome ...
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    The role of mycobacterium tuberculosis antigen specific cytokines in determination of acid fast bacilli culture status in pulmonary tuberculosis patients co-infected with human immunodeficiency virus 

    Kisuya, Job; Chemtai, Alex; Raballah, Evans; Okumu, Wilson; Keter, Alfred; Ouma, Collins (The Pan African Medical Journal, 2018-11-08)
    Introduction: the interaction between Mycobacterium tuberculosis and HIV leads to rapid progression of tuberculosis (TB) and human immunodeficiency virus (HIV)-induced immunosuppression. Diagnosis of TB in these patients ...
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    Genetic variation in CSF2 (5q31.1) is associated with longitudinal susceptibility to pediatric malaria, severe malarial anemia, and all-cause mortality in a high-burden malaria and HIV region of Kenya 

    Kisia, Lily E.; Cheng, Qiuying; Raballah, Evans; Munde, Elly O.; McMahon, Benjamin H.; Hengartner, Nick W.; Ong’echa, John M.; Chelimo, Kiprotich; Lambert, Christophe G.; Ouma, Collins; Kempaiah, Prakasha; Perkins, Douglas J.; Schneider, Kristan A.; Anyona, Samuel B. (Tropical Medicine and Health, 2022-06-25)
    Plasmodium falciparum infections remain among the leading causes of morbidity and mortality in holoendemic transmission areas. Located within region 5q31.1, the colony-stimulating factor 2 gene (CSF2) encodes granulocyte ...
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    The diagnostic accuracy of Th1 (IFN-γ, TNF-α, and IL-2) and Th2 (IL-4, IL-6 and IL-10) cytokines response in AFB microscopy smear negative PTB- HIV co-infected patients 

    Kisuya, Job; Chemtai, Alex; Raballah, Evans; Keter, Alfred; Ouma, Collins (Microbiology Resource Announcements, 2019-04)
    Acid Fast Bacilli (AFB) microscopy smear remains the most widely used laboratory diagnostic technique for Pulmonary Tuberculosis (PTB) in low-and-middle income countries. Although it is highly specific, the sensitivity ...
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    Differential Gene Expression in Host Ubiquitination Processes in Childhood Malarial Anemia 

    Anyona, Samuel B.; Raballah, Evans; Cheng, Qiuying; Hurwitz, Ivy; Ndege, Caroline; Munde, Elly; Otieno, Walter; Seidenberg, Philip D.; Schneider, Kristan A.; Lambert, Christophe G.; McMahon, Benjamin H.; Ouma, Collins; Perkins, Douglas J. (Frontiers in Genetics, 2021-11-22)
    Background: Malaria remains one of the leading global causes of childhood morbidity and mortality. In holoendemic Plasmodium falciparum transmission regions, such as western Kenya, severe malarial anemia [SMA, hemoglobin ...
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    Raballah, Evans (38)
    Ouma, Collins (27)Cheng, Qiuying (17)Perkins, Douglas J. (16)Anyona, Samuel B. (13)Munde, Elly O. (11)Perkins, Douglas J (9)Anyona, Samuel B (8)McMahon, Benjamin H. (8)Okumu, Wilson (8)... View MoreSubjectHematological, profiles, newly, diagnosed, pulmonary, tuberculosis, patients, Western (2)CD4 T-cell, expression , IFN-γ, IL-17, pediatric, malarial, anemia (1)Changes , frequencies, Plasmodium, falciparum, dhps , dhfr drug-resistant, mutations, children ,Western, Kenya from 2005 to 2018: the rise of Pfdhps S436H (1)Changes,frequencies,Plasmodium, falciparum, dhps, dhfr, drug-resistant, mutations, children, Western 2005, 2018, rise, Pfdhps S436H (1)Comparative, genomic , phenotypic, characterization ,invasive, non-typhoidal ,Salmonella, isolates (1)Complement, component, 3 mutations ,alter, longitudinal, risk, pediatric, malaria, severe, malarial, anemia (1)Cyclooxygenase-2, haplotypes, longitudinal, risk , malaria ,severe ,malarial, anemia, Kenyan, children, holoendemic ,transmission, region (1)Diagnostic, accuracy, Th1 (IFN-γ, TNF-α, and IL-2) Th2 (IL-4, IL-6 ,IL-10) cytokines, response , AFB, microscopy, smear, negative, PTB- HIV co-infected, patients (1)Differential, Gene, Expression, Host, Ubiquitination, Processes, Childhood, Malarial, Anemia (1)Direct, detection, bacteremia, exploiting, host-pathogen, interactions, lipoteichoic, acid, lipopolysaccharide (1)... View MoreDate Issued2020 - 2024 (17)2012 - 2019 (21)Has File(s)Yes (38)

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