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Molecular Characterization of Indigenous Rhizobia from Kenyan Soils Nodulating with Common Beans
(International Journal of Molecular Sciences, 2023-05-30)
: Kenya is the seventh most prominent producer of common beans globally and the second
leading producer in East Africa. However, the annual national productivity is low due to insufficient
quantities of vital nutrients ...
In Silico Identification of New Anti-SARS-CoV-2 Main Protease (Mpro) Molecules with Pharmacokinetic Properties from Natural Sources Using Molecular Dynamics (MD) Simulations and Hierarchical Virtual Screening
(HINDAWI, 2022-10-10)
Infectious agents such as SARS-CoV, MERS-CoV, and SARS-CoV-2 have emerged in recent years causing epidemics with high mortality rates. The quick development of novel therapeutic compounds is required in the fight against ...
Mutational signatures for breast cancer diagnosis using artificial intelligence
(Journal of the Egyptian National Cancer Institute, 2023-05-15)
Background
Breast cancer is the most common female cancer worldwide. Its diagnosis and prognosis remain scanty, imprecise, and poorly documented. Previous studies have indicated that some genetic mutational signatures are ...
Occurrence, distribution, incidence, and severity of common bean viral diseases in resource-limited smallholder farms of western Kenya
(Crop Protection, 2025-04-09)
The common bean (Phaseolus vulgaris L.) is a vital pulse crop in Kenya, supporting over 300 million people in East Africa and Latin America with its high protein and starch content. However, bean production in Kenya is ...
Monkeypox: genetic, clinical, molecular, diagnostic, and therapeutic perspectives
(Journal of Rare Diseases, 2024-06-17)
Monkeypox is a DNA virus that belongs to the orthopox virus family with two distinct clades known as West African and Congo Basin. This virus was initially discovered in crab-eating Macaques in 1958 and in 1970s it spread ...
Molecular Footprints of Potato Virus Y Isolate Infecting Potatoes (Solanum tuberosum) in Kenya
(Wiley Advances in Virology, 2024-08-06)
Potato virus Y (PVY) is a highly diverse and genetically variable virus with various strains. Differential evolutionary routes have been reported in the genus Potyvirus, caused by natural selection pressure, mutation, and ...
Ligand-based pharmacophore modeling, virtual screening, and molecular dynamics simulations of Pfhsp90 fingerprints in Plasmodium malaria treatment
(Computational and Structural Biotechnology Reports, 2024-10-06)
The World Health Organization (WHO) documents malaria as one of the leading causes of high morbidity and mortality worldwide. The disease affects millions and kills thousands of people annually. Efforts to reduce the global ...
Spatio-temporal characterization of malaria prevalence in a peri-urban resource limited setting of Western Kenya Highlands
(African Health Sciences, 2024-10-06)
Background: Malaria is the main killer disease in sub-Sahara Africa.
Objective: The study identified malaria prevalence patterns in relation to space and time trends in a peri-urban resource limited setting of Western ...
Effect of socio-economic factors on malaria prevalence in a Peri-urban setting in Vihiga County, Western Kenya Highlands
(African Health Sciences, 2024-07-11)
Background: Malaria is the leading cause of mortality in sub-Saharan Africa.
Objective: The study assessed the effect of socio-economic factors on high malaria prevalence in a peri-urban setting in Vihiga County, ...